Pioneering Seizure Detection Using Eye Tracking | Dr. Rachel Kuperman MD

Our guest on this show is Dr. Rachel Kuperman MD, the CEO and Founder of Eysz, a medtech/AI startup that is transforming neurological care. Eysz has developed innovative software that analyzes eye movements and uses those movements as biomarkers to assess brain health across a range of neurological conditions, with an initial focus on epilepsy.

We get to hear from Rachel how the combination of her experiences caring for children with epilepsy combined with her understanding of technology and medicine as well as sheer persistence, resilience and willingness to adapt has led to her current business success.

We discuss topics such as:

• Epilepsy and AI innovation - measuring and managing neurological diseases
• Building a Team/Networking for your startup
• Entrepreneurship, funding, and confidence as a woman in tech.
• Creating an MVP or Minimum Viable Product and adopting the Lean Startup methodology
• The power of storytelling and igniting emotion in the health tech world
• Combining persistence and resilience with openness and adaptability

Host Ranjani Rangan provides important context and draws out Dr. Kuperman’s very personal narrative – from her love of treating patients to her frustration with the limits she encountered when it came to effectively improving their quality of life. 

Interested in learning more? Visit this link to read her blog, including “Journey of a Burnt Out Neurologist,” and contact Eysz for more information about progress in the treatment of epilepsy.

Visit this link to listen to, rate and review Digital Health Disruptors on your preferred streaming platform. You can also click here to schedule a demo of Charm Health’s innovative suite of healthcare products.

KEY TAKEAWAYS:

• (01:20) NEUROLOGIST ON A MISSION: About Dr. Rachel Kuperman and how she came to devote herself to developing a leading-edge medical device to treat epilepsy.
• (03:06) THE PROMISE OF EYSZ: Understanding a world in which 1 in 26 people have epilepsy and defining the uncertainty and stigma they face as a result of  seizures.  
• (04:10) BREAKING DOWN TYPES OF SEIZURES:
  • Convulsive seizures – involving the whole brain, the body dropping to the floor.
  • Absence seizures – involving the whole brain, brief loss of consciousness. 
  • Focal seizures – involving only part of the brain, impairing consciousness.
• (05:17) FROM NEUROLOGIST TO MED TECH ENTREPRENEUR: How the limits of medicine inspired Dr. Kuperman to embrace start-up innovation.
• (07:00) DATA IS THE FIRST STEP! About the power of quantifying not just numbers of seizures but related symptoms to create targeted treatments and measurable results.
• (09:50) IDEA INTO ACTION: How Dr. Kuperman migrated from innovating diagnostic tools in her practice to leaping into start-up culture – and personal growth!
• (12:16) LOOKING AT EYSZ: About how the team is building an FDA-approved Hyperventilation Recorder that leverages predictive data about Absence seizures.
• (14:00) BREAKING BOUNDS: A look at the technological advances and key partners that are accelerating Eysz’s remarkable med tech solutions.
• (15:07) MAKING THE MVP (Minimum Viable Product) JOURNEY:  What it looks like to use rapid iterations and ongoing customer feedback for agile product development.
• (18:14) MORE ABOUT EYSZ’S DEBUT PRODUCT: A phone app that diagnoses childhood seizures and is continuously evolving to become more user-friendly for kids and valuable for diagnosticians.
• (19:00) SYSTEMIC BIAS: What Dr. Kuperman has observed as a female entrepreneur and why the disparity in funding for women in tech is unmistakable – and unacceptable.
• (22:23) STAYING INTEGRAL:  A closer look at the tension between serving public health and making money for investors, who are eager to scale .
• (23:00) THE IMPORTANCE OF STORYTELLING:  Why Eysz’s messaging emphasizes the experience of children with epilepsy to improve communication with their physicians as well as increase resonance and impact among the public at large.
• (24:50) KEY GOALS ON EYSZ’S RADAR:
  • Empowering patients to communicate more clearly – and measurably – what they are experiencing as a result of their seizures and related symptoms.
  • Providing valuable data to support and lower risk for pharmaceutical companies undertaking the development of new drugs.
• (25:50) DR. KUPERMAN’S INGREDIENTS FOR SELF-TRUST – AND SUCCESS!
  • Be willing to fail – and be rejected – repeatedly!
  • Be willing to hear feedback, even when it bites.
  • Have the humility to accept that you don’t know everything.
  • Trust in your gut that what you know, you know.
  • Keep on going – even when it’s hard!
• (27:40) INFO INTO ACTION: Why Dr. Kuperman believes getting out there and talking to people is the best way to bust through analysis paralysis, fill in critical data points and validate what you need to support your product, its purpose and claims.

RELEVANT LINKS/FURTHER RESOURCES

• Click here to get more stats and insights about women in business. 
• Further info about the referenced PitchBook-NVCA Venture Monitor.
• More about Steve Blanks’ MVP (Minimum Viable Product) thought leadership available at this link.

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